学部概况
教师队伍
人才培养
学院、部
临床医院
科学研究
管理服务
交流合作
北医产业
ENGLISH
 
 
 
 招生就业
 招聘信息
 校园文化
 服务平台
 校内信息
 信息周刊
首页 >> 学术讲座 >>

(6月28日)北京大学基础医学院院长论坛
发布日期:2017-06-26 浏览次数: 字号:[ ]

  报告题目: A novel KDM4 inhibitor controls triple-negative breast

  cancer stem cells.

  报告人: Prof. Dr. Roland Schuele

  Professor, Scientific Director, Dept. of Urology and

  Director, Center for Clinical Research

  Freiburg University Medical Centre

  Germany.

  Speaker CRC 992 Medical Epigenetics.

  时间: 2017 年 6 月 28 日(星期三) 下午 14:00

  地点: 生化楼三层中厅

  主持人: 细胞生物学系 杜晓娟 教授

  报告人近年主要发表文章:

  1. Duteil, D., Tosic, M., Willmann, W., Georgiadi, A., Kanouni, T. and

  Schüle, R. (2017) Lsd1 prevents age-programed loss of beige

  adipocytes. Proc. Natl. Acad. Sci. USA, in press.

  2. Metzger E, Willmann D, McMillan J, Forne I, Petroll K, Metzger P,

  Gerhardt S, Maessenhausen A, Schott A-K, Espejo A, Eberlin A,

  Wohlwend D, Schüle KM, Schleicher M, Perner S, Bedford MT, Jung

  M, Dengjel J, Flaig R, Imhof A, Einsle O and Schüle R. Assembly of

  methylated LSD1 and CHD1 drives ARdependent transcription and

  translocation. Nat Struct Mol Biol., 23, 132-139, 2016.

  3. Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N,

  Greschik H, Günther T, Buettner R, Talianidis I, Metzger D and Schüle

  R. LSD1 promotes oxidative metabolism of white adipose tissue. Nat

  Commun. 5, 4093, 2014

  4. Zhu D, H?lz S, Metzger E, Pavlovic M, Jandausch A, Jilg C, Galgoczy

  P, Herz C, Moser M, Metzger D,ünther T, Arnold SJ and Schüle R. Lsd1

  regulates differentiation onset and migration of trophoblast stem cells.

  Nat. Commun. 5, 3174-3184, 2014.

  5. Metzger E, Imhof A, Patel D, Kahl K, Hoffmeyer K, Friedrichs F,

  Müller JM, Greschik H, Kirfel J, Ji S, Kunowska N, Beisenherz-Huss

  C, Günther T, Buettner R and Schüle R. Phosphorylation of histone

  H3T6 by PKCβI controls demethylation at histone H3K4. Nature 464,

  792-796, 2010.

  6. Metzger E, Wissmann M, Yin N, Müller JM, Schneider R, Peters HFM,

  Günther T, Buettner R and Schüle R. LSD1 demethylates repressive

  histone marks to promote androgen receptor dependent transcription.

  Nature 437, 436-439, 2005.




打印本页 关闭窗口

版权所有:北京大学医学部 北京市海淀区学院路38号  邮编:100191  京ICP备05065075号-19